G protein-coupled receptors

Sandra Siehler

at 250 WPM

7h 26m

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15

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446

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G protein-coupled receptors

by Sandra Siehler, Graeme Milligan

2010

Cambridge University Press

446

9780521112086

Description

"This text provides a comprehensive overview of recent discoveries and current understandings of G protein-coupled receptors (GPCRs). Recent advances include the first mammalian non-rhodopsin GPCR structures and reconstitution of purified GPCRs into membrane discs for defined studies, novel signaling features including oligomerization, and advances in understanding the complex ligand pharmacology and physiology of GPCRs, in new assay technologies and drug targeting. The first chapters of this book illustrate the history of GPCRs based on distinct species and genomic information. This is followed by discussion of the homo- and hetero-oligomerization features of GPCRs, including receptors for glutamate, GABAB, dopamine, and chemokines. Several chapters are devoted to the key signaling features of GPCRs. The authors take time to detail the importance of the pathophysiological function and drug targeting of GPCRs, specifically -adrenoceptors in cardiovascular and respiratory diseases, metabotropic glutamate receptors in CNS disorders, S1P receptors in the immune system, and Wnt/Frizzled receptors in osteoporosis"--Provided by publisher.

Frequently Asked Questions

How many pages are in G protein-coupled receptors?

This edition of G protein-coupled receptors has approximately 446 pages. Please note, this is an estimate and the exact page count can vary between hardcover, paperback, and e-book versions.

How long does it take to read G protein-coupled receptors?

For most readers, G protein-coupled receptors typically takes between 9h 18m and 6h 12m to complete. This is based on the book's length of approximately 111,500 words and common reading speeds.

Here's a detailed breakdown: • Continuous reading at 250 WPM: approximately 7h 26m of focused reading • Casual reading (30 minutes/day): you could finish in roughly 15 days • Estimated word count: 111,500 words

Your individual reading time will vary based on your personal reading pace, the amount of daily reading time, and your familiarity with the subject matter.

What is the word count of G protein-coupled receptors?

The estimated word count for G protein-coupled receptors is approximately 111,500 words. This figure is calculated using industry-standard methods that consider genre-specific word density patterns, typical formatting and layout characteristics, and standard words-per-page ratios for published books.

This is an approximation — actual word count may vary based on font size, formatting, edition, and the presence of illustrations or charts.

Who is the author of G protein-coupled receptors?

G protein-coupled receptors was written by Sandra Siehler, Graeme Milligan.

When was G protein-coupled receptors published?

The publication date for this specific edition is 2010. The original work may have been published on a different date.